Y. Pierre Gobin, M.D.

Vascular and Interventional Radiology

Publications

Brain Aneurysms

- Intraprocedural aneurysm rupture during coil embolization of brain aneurysms: role of balloon assisted coiling. AJNR 2012. 10.3174/ajnr.A3061

- Balloon-assisted coil embolization of intracranial aneurysms is not associated with increased periprocedural complications. J NeuroIntervent Surg (2012). Doi:10.1136/neurintsurg-2012-010351

- Early endovascular management of oculomotor nerve palsy associated with posterior communicating artery aneurysms. Interventional Neuroradiology 2010;16:17-21
- Principles in case-based aneurysm treatment: approaching complex lesions excluded by international subarachnoid aneurysm trial (ISAT) criteria. World Neurosurg 2011;75:462-475

- Transluminal balloon angioplasty for symptomatic distal vasospasm refractory to medical therapy in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2011;69:95-102

-Endovascular management of distal anterior inferior cerebellar artery aneurysms: report of two cases and review of the literature. Surg Neurol Int 2011;2:950

- Bare platinum vs matrix detachable coils for the endovascular treatment of intracranial aneurysms: a multivariate logistic regression analysis and review of the literature. Neurosurgery 2011;69:557-565
- Intra-procedural aneurysm rupture treated with n-butyl cyanoacrylate embolization: technical note. J NeuroIntervent Surg 2009
- Balloon-assisted technique for trapped microcatheter retrieval following onyx embolization. Interventional Neuroradiology 2009 15:453-455

- Intraprocedural aneurysm rupture treated with n-butyl cyanoacrylate embolization: technical note. J Neurointervent Surg 2010;2:145-146

- Neuroform Stent-assisted Coil Embolization of Wide-neck Intracranial Aneurysms: Strategies in - Stent Deployment and Mid-Term Follow Up. Neurosurgery 2007;61:460-469

Disappearance and reappearance of a cerebral aneurysm: a case report. Surgical Neurology (67) 2007 186–9.
- Treatment of a giant vertebrobasilar artery aneurysm using stent grafts. J Neurosurgery 107:165-168, 2007.
- Is routine intraoperative angiography in the surgical treatment of cerebral aneurysms justified? A consecutive series of 147 aneurysms and review of the literature. Neurosurg. 2006;58:719-726.

- Vasospasm in aneurysmal subarachnoid hemorrhage: diagnosis, prevention and management. In Neuroimaging Clin N Am. 2006;16:483-497.

- Treatment of Ruptured Intracranial Aneurysms: looking to the past to register the future. Neurosurgery 2006;59: 1157-1167.

- Endovascular Techniques for Treating Wide-Necked Aneuryms. Neurosurg Focus, 18 (2):E7, 2005

- Advances in endovascular aneurysm treatment: are we making a difference? Neuroradiology 2005;47:695-701

- Treatment of unruptured aneurysms with GDCs: clinical experience with 247 aneurysms. AJNR American Journal of Neuroradiology 2004; 25(4):577-83.

- Endovascular management of dolichoectasia of posterior cerebral artery. AJNR 2004;25:1790-1791.

- Guglielmi detachable coil embolization of cerebral aneurysms: 11 year's experience. J Neurosurgery 2003;98:959-66.

- Combined endovascular treatment for both intracranial aneurysms and symptomatic vasospasm. AJNR 2003; 24:133-9.

- Three-dimensional helical computerized tomography angiography in the diagnosis, characterization, and management of middle cerebral artery aneurysms: comparison with conventional angiography and intraoperative findings. J Neurosurgery 97:1322-1332,2002

- Endovascular treatment of basilar artery trunk aneurysms with Guglielmi detachable coils: clinical experience with 41 aneurysms in 39 patients. J Neurosurg. 2001;95:624-32.

- Volume-rendered helical computerized tomography angiography in the detection and characterization of intracranial aneurysms. J Neurosurgery 2000;93:254-264.

- Natural history of the neck remnant of cerebral aneurysms treated with the Guglielmi detachable coil system. J. Neurosurgery 2000;93:561-568.

- Endovascular treatment of basilar tip aneurysms using Guglielmi detachable coils: anatomic and clinical outcomes in 73 patients from a single institution. Neurosurgery 2000;47:1332-1342.

- Endovascular Treatment of Ruptured Aneurysms. Critical Care Clinics of North America 1999;15 (4):667-685.

- Endovascular treatment of multiple intracranial aneurysms by using Guglielmi detachable coils. J. Neurosurgery 1999; 90(5):857-64.

- Balloon-asssisted Guglielmi detachable coiling of wide necked aneurysms. Part I: Experimental results. Neurosurgery 1999;45:519-530

- Balloon-asssisted Guglielmi detachable coiling of wide necked aneurysms. Part II: Clinical results. Neurosurgery 1999;45:531-538.

- Embolization of incidental cerebral aneurysms by using the Guglielmi detachable coil system. J Neurosurgery 90:207-214,1999.

- Unruptured aneurysms presenting with mass effect symptoms: response to endosaccular GDC treatment. Part 1: symptoms of cranial nerve dysfunction. J Neurosurgery 1998;89:956-61.

- Intracranial aneurysms treated with the Guglielmi detachable coil: midterm clinical results in a consecutive series of 100 patients. J Neurosurg 1997;87:176-183.

- Incidence of cerebral vasospasm after endovascular treatment of acutely ruptured aneurysms: report on 69 cases. J Neurosurg 1997;87:830-35.

- Endovascular therapy of superior hypophyseal artery aneurysms: Embolization with electrolycally detachable coils. Neurosurgery 1996; 39:1150-1154.

- Treatment of large and giant fusiform intracranial aneurysms with Guglielmi detachable coils. J Neurosurg 1996;84:55-62.

- Aneurysmal rupture after parent vessel sacrifice: treatment with GDC coil embolization via retrograde catheterization: Case report. Neurosurgery 1995;37(6):1216-21.

- Selective endovascular treatment of 71 intracranial aneurysms with platinium coils. J Neurosurg 1993;79:3-10.

- Balloon occlusion of the internal carotid artery in 40 cases of giant intracavernous aneurysms: technical aspects, cerebral monitoring and results. Neuroradiology 1992; 34:245-251.

- Endovascular occlusion of vertebral arteries in the treatment of unclippable vertebro-basilar aneurysms.Neurosurgery 1991; 74:393-398.

- Endovascular Occlusion of Intracranial Vessels for Curative Treatment of Unclippable Aneurysms: report of 16 cases. J Neurosurgery 1991; 75:694-702.

Retinoblastoma

- Artery Chemosurgery for Retinoblastoma Prevents New Intraocular Tumors.Abramson DH, et al. Show Ophthalmology. 2012 Nov 20. pii: S0161-6420(12)00806-8. doi: 10.1016/j.ophtha.2012.08.023.

- Intraocular hemorrhage after intra-arterial chemotherapy for retinoblastoma in sickle cell trait. Open Ophthalmology J 2012;6:1-3

- Combined sequential intravenous and intra-arterial chemotherapy (bridge chemotherapy) for young infants with retinoblastoma. PLOS ONE Sept 2012; Vol 7 Issue 9: e44322

- Experience of intra-arterial chemosurgery with single agent carboplatin for retinoblastoma. Br J Ophthalmol doi:10.1136/bjophthalmol-2012-301686

- Intra-arterial chemotherapy for retinoblastoma in eyes with vitreous and/or subretinal seeding: 2-year results. Br J Ophthalmol 2012 96:499-502

- Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomy. Arch Ophthalmol 2012;130:180-185

- ERG monitoring of retinal function during systemic chemotherapy for retinoblastoma. Br J Ophthalmol 2012 Mar 18 [Epub ahead of print]

- Ophthalmic artery chemosurgery for he management of retinoblastoma in eyes with extensive (>50%) retinal detachment. Pediatr Blood Cancer 2012 April 10 [Epub ahead of print]

- Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review. PLoS ONE 7(4): e34120.doi:10.1371/journal.pone.0034120

- Radiation exposure during intra-arterial chemotherapy for retinoblastoma. Arch Ophthalmol 2012;130:403-404

- Intra-arterial chemotherapy for retinoblastoma. Ophthalmology 2012; 119:1720-1721

- Histopathological findings of eyes enucleated after treatment with chemosurgery for retinoblastoma. The Open Ophthal J 2011;5:1-5

- Intra-arterial chemotherapy for the management of retinoblastoma. Four-year experience. Arch Ophthalmol 2011;129:732-737

- Intra-arterial and oral digoxin therapy for retinoblastoma. Ophth Gen Online March 29, 2011

- Superselective ophthalmic artery chemotherapy as primary treatment for retinoblastoma (chemosurgery). Ophthalmology 2010;117:1623-9

- Spontaneously resolving periocular erythema and ciliary madarosis following intra-arterial chemotherapy for retinoblastoma. Middle East African Journal of Ophthalmology 2010;17:207-9.
- Bilateral superselective ophthalmic artery chemotherapy for bilateral retinoblastoma: tandem therapy. Arch Ophthalmol 2010;128:370-372

- Persistence of retinal function after selective ophthalmic artery chemotherapy infusion for retinoblastoma. Documenta Ophthalmologica 2009;119:13-22

- A Phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with Melphalan for intraocular retinoblastoma. Ophthalmology 2008;115:1398-1404.

Brain Arteriovenous malformations and Fistulas

- Bilateral thalamic venous hypertension caused by a tentorial dural arteriovenous fistula: endovascular treatment. J Neurol Neurosurg Psych 2011

- Intracranial dural arteriovenous fistula presenting as an enhancing lesion of the medulla. JNIS 2010;2:390-393

- Transient aphasia and reversible major depression due to a giant sagittal sinus dural AV fistula. Neurology. 61(4):557-8, 2003.

- The New York Islands AVM study: design, study progress, and initial results. Stroke 2003; 34:e29-33. Adult pial arteriovenous fistula and superior sagittal sinus stenosis: angiographic evidence for high flow venopathy at an atypical location. J Neurosurgery 2002;96:792-5.

- Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients. Neurosurgery 2001;48:984-95.

- Dural arteriovenous fistula in children: endovascular treatment and outcomes in seven cases. AJNR 2001;22:1217-25.

- Transvenous embolization of a dural arteriovenous fistula of the cavernous sinus through the contralateral pterygoid plexus. Neuroradiology 1998;40:189-193.

- Endovascular treatment of Intracranial Dural Arteriovenous Malformations. Journal of Stroke and Cerebrovascular Disease 1997:6;295-298

- Embolization of dural cavernous fistulas via superior ophthalmic vein approach.AJNR 1997;18:921-8.

- Treatment of brain arteriovenous malformations by embolization and radiosurgery. J Neurosurgery 1996;85:19-28.

- Intracranial dural arteriovenous fistulas with spinal venous drainage: relation between clinical presentation and angiographic findings. AJNR 1996;17:1549-1554.

- Cerebral dural arteriovenous fistulas: Clinical and angiographic correlation with a revised classification of venous drainage. Radiology 1995; 194:671-680.

- A Proposed Angiographic Classification of Intracranial Arteriovenous Fistulae and Malformations. Neuroradiology 1993;35:381-385.

- Percutaneous Transvenous Embolization through the Thrombosed Sinus in Transverse Sinus Dural Fistulas. AJNR 1993;14:1102-1105.

- Endovascular Treatment of intracranial dural arteriovenous fistulas with spinal perimedullary venous drainage. J Neurosurgery 1992; 77:718-723.

Spinal Cord Arteriovenous Malformations and Fistulas

- Vascular anatomy of the spinal cord. J Neurointervent Surg 2012;4:67-74

- Endovascular treatment of spinal arteriovenous lesions : beyond the dural fistula. AJNR 2011;32:798 808
- Secondary clinical deterioration after successful embolization of a spinal dural arteriovenous fistula: a plea for anticoagulation. Interventional Neuroradiology 2010;16:199-203

- Endovascular Surgery for Vascular Malformations of the Spinal Cord. Operative Techniques in Neurosurgery, Vol 6, No 3 (September), 2003: pp163-170. Elsevier Science

- N-butyl cyanoacrylate embolization of spinal dural arteriovenous fistulae. AJNR 2001;22:40-47.

- Surgical and endovascular treatment of spinal dural arteriovenous fistulas: long-term disability assessment and prognostic factors. J. Neurosurgery 2001; 94:199-204.

- Two concurrent spinal dural arteriovenous fistulae in a patient with rapidly progressive myelopathy. A case report. Angiology 1995;46(3):251-7.

- Giant perimedullary arteriovenous fistulas of the spine: clinical and radiological features and endovascular treatment.AJNR 1997;18:677-687.

- Classification and Endovascular Treatment of Spinal Cord Arteriovenous Malformations and Fistulas. Journal of Stroke and Cerebrovascular Disease 1997:6;282-286.

- Intracranial dural arteriovenous fistulas with spinal venous drainage: relation between clinical presentation and angiographic findings. AJNR 1996;17:1549-1554.

- Intradural Perimedullary Arteriovenous Fistulae : Results of Surgical and Endovascular Treatment in a Series of 35 Cases. Neurosurgery 1993; 32:885-891.

- Phase-Contrast Magnetic Resonance of the Spinal Cord. Preliminary Results in Spinal Cord Arterio-Venous Malformations. Acta Neurochirurgica 1993;123:57-63.

- Endovascular Therapy for Arteriovenous Malformations and Fistulae in the Spinal cord. Seminars in Interventional Radiology 1993;10:227-242.

- Endovascular Treatment of intracranial dural arteriovenous fistulas with spinal perimedullary venous drainage. J Neurosurgery 1992; 77:718-723.

- Phase-Contrast MR Angiography of Vascular Malformations of the Spinal Cord at 0,5 Tesla. JMRI 1992; 2:631-636.

Superficial Vascular Malformations

- Thoraco-lumbar artery aneurysms associated with a metameric paraspinal lesion presenting with retroperitoneal hemorrhage: endovascular management. Surg Neur Int 2011;2:137

- Percutaneous Puncture of the External Carotid Artery or Its branches after Surgical Ligation. AJNR 1994;15:79-82.

- Curative treatment of scalp arteriovenous fistulas by direct puncture and embolization with absolute alcohol. J Neurosurgery 1991; 75 (4):634-637

- Endovascular Treatment of External Carotid-Jugular Fistulas in the Parotid Region. Neurosurgery 1993; 33:812-816.

Stroke

- Impact of operator and site experience on outcomes after angioplasty and stenting in the SAMMPRIS trial. JNIS 2012;0:1-6. Doi:10.1136/neurointsurg-2012-010504

- Interventional management for secondary intracranial extension of spontaneous cervical arterial dissections. Surg Neurol Int 2010;1:82

- Predictors and timing of hypotension and bradycardia after carotid artery stenting. AJNR 2008; 29:1942-47.

- Mechanical Thrombectomy for Acute Ischemic Stroke. Final Results of the Multi MERCI Trial. Stroke 2008;39:1205-1212.

- The Merci Retriever in acute stroke treatment. Expert Rev Med Devices. 2006; 3:273-80.

- MERCI 1. A phase 1 study of mechanical embolus removal in cerebral ischemia. Stroke 2004;35:2848-2854.

- Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36:1432-1440.

- Mechanical Embolectomy. Neurosurgery Clinics North America 2005,3: 463-474.

- Progressive symptomatic carotid dissection treated with multiple stents. Stroke. 2005 Sep; 36(9):e80-2.

- Beyond tissue plasminogen activator: Mechanical Intervention in Acute Stroke. Ann Emerg Med 2003;41:838-846.

- Validation of computed tomographic middle cerebral artery "dot" sign: an angiographic correlation study. Stroke 2003; 34: 2636-40.

- Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapies. Stroke 2004; 35:e30-4.

- Beyond tissue plasminogen activator: mechanical intervention in acute stroke. Ann Emerg Med 2003; 41:838-46.

- Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infracted tissue. Stroke 2003; 34:1425-30.

- Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol 2002;52:698-703.

- Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke 2002;33:717-24.

- Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging application. Stroke 2002;33:95-8.

- Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humans. Neurology 2001;57:2015-21.

- Endovascular treatment of dural sinus thrombosis with rheolytic thrombectomy and intra-arterial thrombolysis. Stroke 2000;31:1420-1425.

- Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann Neurol 2000;47:462-469.

- Intraarterial thrombolysis for treatment of acute stroke: experience in 26 patients with long-term follow-up.AJNR 1999;20:1291-1299.

- Initial and long-term results of treatment of brachiocephalic arterial stenoses and occlusions with balloon angioplasty, thrombolysis, stents.J Inv Cardiology 1997;9:372-383.

Brain tumors

- Balloon-assisted superselective intra-arterial infusion of bevacizumab for malignant brainstem glioma. Interventional Neuroradiology 2010;16:71-6

- Preoperative embolization in the treatment of choroids plexus papilloma in an infant: Case report. J Neurosurg (6 Suppl Pediatrics) 104:419–421, 2006.

- Intra-Arterial Chemotherapy for Brain Tumors by Using a Spatial Dose Fractionation Algorithm and Pulsatile Delivery. Radiology 2001; 218:724-732.

- Prognostic factors of primary brain tumors treated by intra-arterial chemotherapy. AJNR 2000;21:471-478.

- Intra-arterial Cereport (RMP-7) and carboplatin: a dose escalation study for recurrent malignant gliomas. Neurosurgery 1999;44:270-278.

- Intraarterial carboplatin chemotherapy for brain tumors: A dose escalation study based on cerebral blood flow. J. Neuro-Oncology 1997;35:121-131.

- Intra-carotid infusion of RMP-7, a bradykinin analog, and transport of gallium-68 ethylenediamine tetraacetic acid into human gliomas. J Neurosurgery 1997;86:603-609.

Laboratory

- Orthotopic glioblastoma stem-like cell xenograft model in mice to evaluate intra-arterial delivery of bevacizumab: from bedside to bench. J Clin Neurosci (2012) doi:10.1016/j.jocn.2012.03.012

- Novel microcatheters for selective intra-arterial injection of fluid in the rat brain. AJNR 2009;30:1190-96

- Head and neck hypervascular lesions: Embolization with ethylene vinyl alcohol copolymer- Laboratory evaluation in swine and clinical evaluation in humans. Radiology 2001; 221:309-317

- Embolization with radiopaque microbeads of polyacrylonitrile hydrogel: evaluation in swine. Radiology 2000;214:113-119.

- Development of the biologically active Guglielmi Detachable Coil for the treatment of cerebral aneurysms. Part II: An experimental study in a swine aneurysm model. AJNR 1999;20:1992-1999.

- Intra-arterial administration of carboplatin and the blood brain barrier permeabilizing agent RMP-7: a toxicologic evaluation in swine.J Neuro-Oncology 1998;36:167-178.

- Nonadhesive liquid embolic agent for cerebral arteriovenous malformations: preliminary histopathological studies in swine rete mirabile. Neurosurgery 1998;43:1164-1172.

- Laboratory simulations and training in endovascular embolotherapy with a swine arteriovenous malformation model.AJNR 1996;17:271-279.

- Trisacryl gelatin microspheres for therapeutic embolizations,II: preliminary clinical evaluation in tumors and arteriovenous malformations. AJNR 1996;17:541-549.

- Endovascular treatment of fusiform aneurysms with stents and coils: technical feasibility in a swine model. AJNR 1995;16:1953-63.

- An experimental arteriovenous malformation model in swine: Anatomic basis and construction technique.AJNR 1994; 15:1537-47.

- In vitro study of haemodynamics in a giant saccular aneurysm model: influence of flow dynamics in the parent vessel and effects of coil embolization. Neuroradiology 1994;36:530-36

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