Thangamani Muthukumar, M.D., M.B.,B.S.

Publications

1. Afaneh C, Muthukumar T, Lubetzky M, Ding R, Snopkowski C, Sharma V, Seshan S, Dadhania D, Schwartz JE, Suthanthiran M. Urinary Cell Levels of mRNA for OX40, OX40L, PD-1, PD-L1 or PD-L2 and Acute Rejection of Human Renal Allografts. Transplantation, 2010;90:1381-7.


2. Anglicheau D, Muthukumar T, Suthanthiran M. MicroRNAs: small RNAs with big effects. Transplantation, 2010;90:105-12.


3. Dadhania D, Snopkowski C, Ding R, Muthukumar T, Lee J, Bang H, Sharma VK, Seshan S, August P, Kapur S, Suthanthiran M. Validation of noninvasive diagnosis of BK virus nephropathy and identification of prognostic biomarkers. Transplantation, 2010;90:189-97.


4. Hartono C, Muthukumar T, Suthanthiran M. Noninvasive diagnosis of acute rejection of renal allografts. Curr Opin Organ Transplant, 2010;15:35-41.


5. Dadhania D, Snopkowski C, Ding R, Muthukumar T, Chang C, Aull M, Lee J, Sharma VK, Kapur S, Suthanthiran M. Epidemiology of BK virus in renal allograft recipients: independent risk factors for BK virus replication. Transplantation, 2008;86:521-8.


6. Muthukumar T, Dadhania D, Ding R, Snopkowski C, Naqvi R, Lee JB, Hartono C, Li B, Sharma VK, Seshan SV, Kapur S, Hancock WW, Schwartz JE, Suthanthiran M. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med. 2005;353: 2342-51.


7. Luo X, Yang H, Kim IS, Saint-Hilaire F, Thomas DA, De BP, Ozkaynak E, Muthukumar T, Hancock WW, Crystal RG, Suthanthiran M. Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self- tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice. Transplantation. 2005;79:1091-6.


8. Boffa DJ, Waka J, Thomas D, Suh S, Curran K, Sharma VK, Besada M, Muthukumar T, Yang H, Suthanthiran M, Manova K. Measurement of apoptosis of intact human islets by confocal optical sectioning and stereologic analysis of YO-PRO-1-stained islets. Transplantation. 2005;79:842-5.


9. Tatapudi RR, Muthukumar T, Dadhania D, Ding R, Li B, Sharma VK, Lozada-Pastorio E, Seetharamu N, Hartono C, Serur D, Seshan SV, Kapur S, Hancock WW, Suthanthiran M. Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int. 2004;65:2390-7.


10. Muthukumar T, Palaniappan R, Gnanavelu G, Fernando E, Jayakumar M. QT interval dispersion is increased following hemodialysis in patients with end-stage renal failure. Ind J Nephrology. 2003;13: 135-40.


11. Muthukumar T, Fernando EM, Jayakumar M, Muthusethupathi MA. Familial focal segmental glomerulosclerosis: A report of five families from India. Ind J Nephrology. 2003;13: 126-30.


12. Gupta KL, Muthukumar T, Dotial A, Prasad R, Joshi K, Jha V, Kohli HS, Sud K, Ganguly NK, Sakhuja V. A Study of Tubular Dysfunction in Indian Patients With Lupus Nephritis. Hong Kong J Nephrol. 2003;5:90-97.


13. Medeiros M, Sharma VK, Ding R, Yamaji K, Li B, Muthukumar T, Valderde-Rosas S, Hernandez AM, Munoz R, Suthanthiran M. Optimization of RNA yield, purity and mRNA copy number by treatment of urine cell pellets with RNAlater. J Immunol Methods. 2003;279:135-42.


14. Dadhania D, Muthukumar T, Ding R, Li B, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, Suthanthiran M. Molecular signatures of urinary cells distinguish acute rejection of renal allografts from urinary tract infection. Transplantation. 2003;75:1752-4.


15. Muthukumar T, Ding R, Dadhania D, Medeiros M, Li B, Sharma VK, Hartono C, Serur D, Seshan SV, Volk HD, Reinke P, Kapur S, Suthanthiran M. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation. 2003;75:1565-70.


16. Ding R, Li B, Muthukumar T, Dadhania D, Medeiros M, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, Suthanthiran M. CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation. 2003;75:1307-12.


17. Sakhuja V, Muthukumar T, Sud K, Gupta A, Kohli HS, Jha V, Gupta KL. Vesicoureteric reflux and reflux nephropathy as seen at a tertiary care adult nephrology service in India-an analysis of 86 patients. Ren Fail. 2003;25:173-81.


18. Muthukumar T, Fernando ME, Jayakumar M. Prognostic factors in immunoglobulin-A nephropathy. J Assoc Physicians India. 2002;50:1354-9.


19. Muthukumar T, Jayakumar M, Fernando EM, Muthusethupathi MA. Acute renal failure due to rifampicin: a study of 25 patients. Am J Kidney Dis. 2002;40:690-6.


20. Ding R, Medeiros M, Dadhania D, Muthukumar T, Kracker D, Kong JM, Epstein SR, Sharma VK, Seshan SV, Li B, Suthanthiran M. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation. 2002;74:987-94.


21. Yang H, Thomas D, Boffa DJ, Ding R, Li B, Muthukumar T, Sharma VK, Lagman M, Luo GX, Kapur S, Liou HC, Hancock WW, Suthanthiran M. Enforced c-REL deficiency prolongs survival of islet allografts. Transplantation. 2002;74:291-8.


22. Jha V, Muthukumar T, Kohli HS, Sud K, Gupta KL, Sakhuja V. Impact of cyclosporine withdrawal on living related renal transplants: a single-center experience. Am J Kidney Dis. 2001;37:119-124.


23. Kohli HS, Bhaskaran MC, Muthukumar T, Thennarasu K, Sud K, Jha V, Gupta KL, Sakhuja V. Treatment-related acute renal failure in the elderly: a hospital-based prospective study. Nephrol Dial Transplant. 2000;15:212-7.


24. Sud K, Muthukumar T, Singh B, Garg SK, Kohli HS, Jha V, Gupta KL, Sakhuja V. Isoniazid does not affect bioavailability of cyclosporine in renal transplant recipients. Methods Find Exp Clin Pharmacol. 2000;22:647-9.


25. Muthukumar T, Jha V, Sud A, Wanchoo A, Bambery P, Sakhuja V. Acute renal failure due to nontraumatic rhabdomyolysis following binge drinking. Ren Fail. 1999;21:545-9.


26. Jha V, Muthukumar T, Singh SK, Kohli HS, Sud K, Gupta KL, Sakhuja V. Familial distal renal tubular acidosis. Nephrol Dial Transplant. 1999;14:1334-5.

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