Publications
1. Glass CK, Lipkin SM, Devary OV, Rosenfeld MG. Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell 1989 Nov 17;59(4):697-708
2. Naar AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG. The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell 1991 Jun 28; 65(7):1267-79
3. Lipkin SM, Rosenfeld MG, Glass CK. Regulation of gene expression by thyroid hormones and retinoic acid. Genetic Engineering 1992;14:185-209
4. Lipkin SM, Nelson CA, Glass CK, Rosenfeld MG. A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains. Proc Natl Acad Sci U S A 1992 Feb 15; 89(4):1209-13
5. Lipkin SM, Naar AM, Kalla KA, Sack RA, Rosenfeld MG. Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression. Genes and Development 1993 Sep; 7(9):1674-87
6. Suhr ST, Gil EB, Eriksson PS, Lipkin SM, Liou NH, Gage F. “Development of regulatable transgene expression systems using mammalian and nonmammalian ligands .� J. Cell. Biochemistry 1995 Mar 10 21A:385-385
7. Lipkin SM, Grider TL, Heyman RA, Glass CK, Gage FH. Constitutive retinoid receptors expressed from adenovirus vectors that specifically activate chromosomal target genes required for differentiation of promyelocytic leukemia and teratocarcinoma cells. J Virology 1996 Oct;70(10):7182-9
8. Lipkin, SM, Wang, V., Jacoby, R., Basu, S., Baxevanis, A., Lynch, H., Elliott, R., and Collins, F. “MLH3: A novel DNA mismatch repair gene associated with mammalian microsatellite instability and a colon cancer susceptibility locus in the mouse.� Nature Genetics (Article) 2000 Jan 24(1):27-35.
9. Lipkin SM, Wang V, Stoler DL, Anderson GR, Kirsch I, Hadley D, Lynch HT, Collins FS. “Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: Evidence for somatic mutation in colorectal cancers.� Hum Mutat 2001 May;17(5):389-96
10. Stella A, Wagner A, Shito K, Lipkin SM, Watson P, Guanti G, Lynch HT, Fodde R, Liu B. “A nonsense mutation in MLH1 causes exon skipping in three unrelated HNPCC families.� Cancer Research 2001 Oct 1;61(19):7020-4
11.Lipkin, SM, Moens PB,, Wang, V., Lenzi, M.,Shanmugarajah, D.,Gilgeous, A., Thomas, J. Cheng, J., Touchman, J. Green, E., Schwartzberg, P,.Collins, FS, & Paula E. Cohen “Meiotic arrest and aneuploidy in MLH3 deficient mice Nature Genetics 2002;31: 385-90.
12. Lynch HT, Weisenburger, D., Quinn-Laquer, B. Snyder, C., Lynch JF, D., Lipkin, SM, and Sanger, W.G.“Family with acute myelogenous leukemia, breast, ovarian and gastrointestinal cancer. Cancer Genetics and Cytogenetics, 2002 Aug; 137(1):8-14
13. Kudryavtseva, E., Sugihara, T., Wang, N., Lasso, R., Gudnason, J., Lipkin, SM and Andersen, B.A.“Identification and characterization of Grainyhead-like Epithelial Transactivator (GET-1), a novel mammalian grainyhead-like factor.� Developmental Dynamics 2002 226(4):604-17.
14. Lipkin SM, Chen, J., Hacia, J., Fodor, S., Rennert, G. and Gruber, S. “Novel DNA Mismatch Repair Gene Variants Associated With Microsatellite Stable Population Based Colorectal Cancer.� Nature Genetics 2004 36: 694-9.
15. Lipkin SM. “Cancer Genetics in Patients of Jewish Ethnicity.� Familial Cancer 2004 Nov 3: 175.16. 16. 16. Domcheck, S., Rebbeck, T., Lipkin S.M and Tucker, M. “Risk Modifiers in Hereditary Cancer Syndromes.� Journal of Clinical Oncology Supplement 89-97, 2005.
17. Shin, BY, Rozek, L., Paxton, L., Peel, D., Anton-Culver, H., Rennert, G., Goodfellow, P., Gruber, S., Lipkin SM. “Low Allele Frequency of MLH1 D132H in American Colorectal and Endometrial Cancer Patients� Dis. of the Colon and Rectum 2005 48: 1723-7.
18. Rozek, L., Lipkin, SM, Fearon E., Hanash, S., Giordano T., Greenson J., Kuick R., Misek, D., Taylor J., Douglas, J., Rennert, G., and Gruber S. “CDX2 Polymorphisms, RNA Expression, and Risk of Colorectal Cancer� Cancer Research 2005 65(13):5488-92.
19. Chen, J., Kuriaguchi, M., Reichow, D., Dudley, S., Arnheim. N., Liskay, RM and Lipkin SM. “Contributions by MutL Homologues Mlh3 and Pms2 to DNA Mismatch Repair and Tumor Suppression in the Mouse.� Cancer Research 2005 65(19):8662-7065.
20. Kolas, N., Svetlanov, A, Lenzi, M., Macaluso, F., Lipkin, S.M., Liskay, R.M, Greally, J., Edelmann, W. and Cohen, P. “Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.� J. Cell Biology 2005 171(3):447-58
21. J. L. Velasquez and S. M. Lipkin" "What Are SNPs and Haplotypes and How Will They Help Us Manage the Prevention of Adult Cancer?" Curr Oncol Rep 2005 7(6) 475-9.
22. Cannavo, E., Marra, G., Sabatés-Bellver, J., Menigatti, M., Lipkin, S.M. Fischer, S., Cejka, P., and Jiricny, J. “Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.� Cancer Research 2005 65(23):10759-66.
23. Wu, X., Tsai, C., Patam, M., Zan, H., Chen, J., Lipkin, S.M. and Casali, P. “A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation.� Journal of Immunology 176: 5426-37.
24. S.A. Frank, Chen, J., and Lipkin, S.M. “Kinetics of cancer: a method to test hypotheses of genetic causation� BMC Cancer 2005 Dec 21;5:163 .
25. Chao, L. and Lipkin, SM. “Molecular Models for the Tissue Specificity of DNA Mismatch Repair Deficient Carcinogenesis.� Nucleic Acids Research 2006 Feb 6;34(3):840-52.
26. Nguyen, H., Tran, A., Lipkin S.M. and John P. Fruehauf “Pharmacogenomics of Colorectal Cancer Prevention and Treatment.� Cancer Investigation 2006 6:24.
27. Lipkin, SM, Boman, B. and Offit, K. “Hereditary Colorectal Cancer: New Advances and the Integration of Molecular Testing into Clinical Practice.� Journal of Clinical Oncology Supplement 2006 42:64-66
28. Zell, JA, Rhee,JM, Ziogas, A, Lipkin,SM and Anton-Culver, H. “Race, Socioeconomic Status, Treatment, and Survival Time among Pancreatic Cancer Cases in California.� Cancer Epidemiol Biomarkers Prev 2007;16(3). March 2007
29. Zishu, P., Sikandar, S., Witherspoon, M., Dizon, D., Bernischke, K., Vrana, P., and Lipkin, SM. Impaired Placental Trophoblast Lineage Differentiation in Alkbh1-/- mice. Developmental Dynamics February 2008.
30. Chao, E, Velasquez, J, Ng, P, Peel, D, Anton-Culver, H, Gruber, SB and Lipkin, SM. “MAPP-MMR: A Novel in silico Approach to Distinguish Deleterious MLH1/MSH2 Missense Mutations from Benign Polymorphisms.� Human Mutation 2008 29(6):852-60.
31. Chen, P., Kuraguchi, M., Velasquez, J., Wang, Y., Yang, K., Edwards, R., Gillen, D., Edelmann, W. Kucherlapati, R., and Steven M. Lipkin� Novel Roles for MLH3 Deficiency and TLE6-like Amplification in DNA Mismatch Repair-Deficient Gastrointestinal Tumorgenesis and Progression.�PLoS Genetics 2008 4(6) e10000921- e100009217.
32. Le H, Ziogas A, Lipkin SM, Zell JA. “Effects of socioeconomic status and treatment disparities in colorectal cancer survival.� Cancer Epidemiol Biomarkers Prev 2008 Aug;17(8):1950-62.
33. Le, H., Rhee, J., Ziogas, A., Lee, JG, Lipkin, SM and Zell, J. “A population-based analysis of pancreatic malignant intraductal papillary mucinous neoplasms (IPMNs). “Cancer Epidemiol Biomarkers Prev 17(10) Oct 2008 2737-2745.
34. Le, H., Ziogas, A., Taylor, T., Lipkin SM, Zell, J. “Survival of distinct Asian groups among colorectal cancer cases in California.� Cancer 115(2), Jan 2009 259-270.
35. Edwards, R., Witherspoon, M., Wang., K, Afrasiabi, K.,Pham, T., Birnbaumer, L. and Lipkin, SM. “Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.� Cancer Research (in press).
