Paul M. Heerdt, M.D., Ph.D.

Anesthesiology

Publications

1.   Heerdt PM, Holmes JW, Cai B, Barbone A, Madigan JD, Reiken SR, Lee DL, Oz MC, Marks AR, Burkhoff D. Chronic unloading by left ventricular assist device (LVAD) reverses abnormal contraction and alters gene expression in end-stage heart failure. Circulation 2000;102-2577-2582.

2.   Blanck TJJ, Haile MJ, Xu F, Zhang J, Heerdt P, Veselis RA, Beckman J, Kang RT, Adamo A, Hemmings HH. Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2 /calmodulin-dependent protein kinase in a canine cardiac arrest model. Anesthesiology 2000;93:1285-1293

3.   Heerdt PM, Blessios G, Beach MJ. Flow-dependency of error associated with thermodilution measurement of cardiac output during tricuspid regurgitation. J Cardiothorac Vasc Anesth 2001; 15(2):183-187

4.   Barbone A, Holmes J, Heerdt PM et al., Comparison of right and left ventricular responses to left ventricular assist device support in patients with severe heart failure: A primary role of mechanical unloading underlying reverse remodeling. Circulation 2001;104(6):670-5.

5.   Heerdt PM, Schlame M, Burkhoff D, Blanck TJJB Disease-specific remodeling of mitochondrial membranes in failing human hearts following unloading by a left ventricular assist device. Ann Thorac Surg 2002;73: 1216-1221

6.   Amar D, Heerdt PM, Korst R, Zhang H, Nguyen. Effects of advanced age on the incidence of supraventricular arrhythmias after pneumonectomy in canines Anesth Analg 2002;94:1132-1136

7.   Schlame M, Towbin JA, Heerdt PM et al., Deficiency of Tetralinoleoyl-Cardiolipin in Barth Syndrome (MIM 302060) Ann Neurol 2002;51:634-637

8.   Koyama Mm Heerdt PM, Levi R. Increased severity of reperfusion arrhythmias in mouse hearts lacking histamine H3-receptors: Evidence for a protective role of H3-receptors in myocardial ischemia. Biochem Biophys Res Commun. 2003 Jul 4;306(3):792-6

9.   Schlame M, Kelley RI, Feigenbaum A, Towbin JA, Heerdt PM, Schieble T, Wanders RJ, DiMauro S, Blanck TJ.. Phospholipid abnormalities in children with Barth syndrome. J Am Coll Cardiol. 2003;42(11):1994-9.

10.   Heerdt PM, Kang R, The A, Hashim M, Mook RJ, Savarese JJ. Cardiopulmonary effects of the novel neuromuscular blocking drug GW280430A in dogs. Anesthesiology 2004; 100:846-851

11.Port JL, Yamaguchi K, Du B, De Lorenzo M, Chang M, Heerdt PM, Kopelovich L, Altorki NK, Subbaramaiah K, Dannenberg AJ. Tobacco Smoke Induces CYP1B1 in the aerodigestive tract, Carcionogenesis 2004; Aug 4 (advance epub)

12.   Heerdt PM. Anesthetics and protein expression. Anesthesiology 2004;101:1040

13.   Memtsoudis S, The AH, Heerdt PM. Autonomic mechanisms in the augmented hypotensive effect of propofol in the elderly. Anesth Analg.2005; 100: 111-115

14.   Heerdt PM, The AH, Markov NP. Anesthetic-induced alteration in expression of myocardial calcium cycling proteins. J Cardiothorac Vasc Anesth 2005;19:340-344

15.   Amar D, Zhang H, Park BJ, Heerdt PM, Fleisher M, Thaler HT. Statin use is accociated with a reduction in atrial fibrillation after thoracic surgery independent of C-reactive protein Chest 2005;128:3421-3427

16.   Heerdt PM, The AH. Cardiomyopathic etiology and SERCA2a reverse remodeling during mechanical support of the failing human heart. Anesth Analg 2006 (in press)

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