Manish A Shah, M.D.

Medical Oncology

Manish A Shah, M.D.

The Gastrointestinal Oncology program at Weill Cornell Medical College/ New York-Presbyterian Hospital offers a comprehensive, multi-disciplinary approach to patients with cancers of the gastrointestinal tract. Gastrointestinal malignancies are among the most common cancers in the United States and around the Globe. Patients with cancers of the GI tract often require expertise across a broad range of disciplines. We are committed to providing personalized and coordinated care in an effort to maximize patient outcomes while minimizing potential side effects of therapy. Advancing the treatment of patients with gastrointestinal malignancies is central to the mission of the Gastrointestinal Oncology Program within the Division of Hematology and Medical Oncology and the Center for Advanced Digestive Care. Additionally, by improving our understanding of the biology of these diseases, including genetic and environmental risks, the role of inflammation and the tumor microenvironment in the development and progression of disease, we hope to improve our ability to prevent, diagnose, and treat these complex diseases.

Dr. Shah graduated from Johns Hopkins University in 1991 with a Bachelor's of Science degree in Biomedical Engineering, and from Harvard Medical School/MIT Health Sciences and Technology program in 1996, graduating magna cum laude, with a Medical Doctorate degree. He completed his Internal Medicine Residency training at Duke University Medical Center in 1999, and his Medical Oncology Fellowship at Memorial Sloan-Kettering Cancer Center in 2001, also serving as Chief Oncology Fellow. He is the recipient of several awards including the American Society of Clinical Oncology Young Investigator and Career Development Awards. He was recruited from Memorial Sloan Kettering Cancer Center to Direct the Gastrointestinal Oncology Program within the Division of Hematology and Medical Oncology and the Center for Advanced Digestive Care at Weill Cornell Medical College / New York-Presbyterian Hospital.

Dr. Shah is a national and international thought leader in drug development and the treatment of gastrointestinal malignancies. He is a distinguished peer-review funded investigator and has led several Phase I, II and III clinical trials in patients with advanced gastric cancer. Dr. Shah is also the Director of the Gastrointestinal Oncology Research Laboratory at Weill Cornell Medical College. His areas of translational research interests are in improving our understanding of cancers of the upper GI tract as well as hereditary gastrointestinal malignancies. He is interested in power of genomic evaluations of malignancy and how the environment and personal risks can impact the genetic causes of malignancy. He is a peer-reviewer for NIH and NCI research funding, and a reviewer for several high impact journals including the Journal of the American Medical Association, Journal of Clinical Oncology, Annals of Surgery, Annals of Surgical Oncology, Clinical Cancer Research and Gastroenterology. Dr. Shah is also the Editor for The Management of Complex Cases in Gastrointestinal Oncology Case Series for the Journal Of Gastrointestinal Oncology and the Series Editor for the Dx/RX: Oncology Series published by Jones and Bartlett Publishers. He has authored several books including Dx/Rx: Upper Gastrointestinal Malignancies: Cancers of the Stomach and Esophagus, as well as 100 Questions and Answers about Stomach Cancer. He is a member of the American Society of Clinical Oncology (serving as a Cancer Education Committee Member), American Association of Cancer Research, and the American Gastroenterology Association. In addition, Dr. Shah is Chair of the Scientific Advisory Board for the DeGregorio Family Foundation for Stomach and Esophageal Cancer Education and Research.

Dr. Shah and the Gastrointestinal Oncology group are committed to providing excellent and personalized care for you and your loved ones. We would welcome the opportunity to take part in your care, whether it involves primary management or for consultation in conjunction with your treating physicians. Ensuring you are receiving the best and most comprehensive treatment for your malignancy is our aim. Please feel free to contact us for an appointment, or have your physician contact us to discuss your care.


Johns Hopkins University (Baltimore MD) B.E.S. Biomedical Engineering 1987 – 1991

Harvard Medical School / Health Sciences and Tech (Boston, MA) MD1991 – 1996

Duke University Medical Center (Durham NC) Internal Medicine Internship 1997

Duke University Medical Center (Durham NC) Internal Medicine Residency 1998-1999

Memorial Sloan-Kettering Cancer Center (NY NY) Medical Oncology Fellow 1999-2001

Memorial Sloan-Kettering Cancer Center (NY NY) Cheif Fellow 2000-2001

Joan and Sanford I. Weill Medical College (NY NY) Fellow in Medicine 1999-2001

PROFESSIONAL MEMBERSHIPS (medical and scientific societies)

Member Cancer and Leukemia Group B (CALGB) 2000-present

Member American Assoc of Cancer Res (AACR) 2000-present

Member American Society of Clin Onc (ASCO) 2000-present

Member American Gastroenterological Association (AGA) 2010-present

Member European Society of Medical Oncology (ESMO) 2010-present

Member Massachusetts Medical Society 1994-1996

Member Tau Beta Pi (Nat'l Engineering Honor Society) 1988-1991
President Tau Beta Pi (JHU Chapter) 1990-1991


NCI External Review Committee – Sept 2005

National Cancer Research Network (United Kingdom, Dept of Health) – Expert External Review Committee – Sept 2005, June 2009

The DeGregorio Family Foundation for Gastroesophageal Cancer, Chair, Scientific Advisory Board – January 2007-present

Peer Review Faculty Reviewer for 2009-present ASCO Educational Book

NIH/ NCI Study Section Member – Panel ZRG1 OTC-K(53) - provide peer review for NICH grant applications in drug delivery for cancer therapy, chemotherapy, and clinical trials.

NIH SBIR Study Section – October 2009 to present

Editorial Board of International Journal of Gastrointestinal Cancer

Case Series Editor – Management of Complex Cases in GI Oncology

2011-2013 ASCO Upper GI Educational Committee Member

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