Joseph Michael Scandura, M.D., Ph.D.

Medical Oncology


 1.   Scandura, J.M. (2005) Advances in the Molecular Genetics of Acute Leukemia. Current Oncology Reports, 7(5):323-32.

2.   Scandura, J.M., Boccuni, P., Massagué, J., Nimer, S.D. (2004) TGFbeta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 upregulation. Proceedings of the National Academy of Sciences, 101(42):15231-6.

3.   MacGrogan, D., Kalakonda, N., Alvarez, S., Scandura, J.M., Boccuni, P., Johansson, B., Nimer, S.D. (2004) Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells. Genes Chromosomes Cancer, 41:203-213.

4.   Boccuni, P., MacGrogan, D., Scandura, J.M. and Nimer, S.D. (2003) The Human L(3)MBT Polycomb Group Protein is a Transcriptional Repressor and Interacts Physically and Functionally with TEL (ETV6). Journal of Biological Chemistry, 278(17):15412-20.

5.   Scandura, J.M., Boccuni, P., Nimer, S.D. (2002) Transcription Factor Fusions in Acute Leukemia: Variations on a Theme. Oncogene, 21(21):3422-44.

6.   Ahmad, S.S., Scandura, J.M. and Walsh, P.N. (2000) Structural and Functional Characterization of Platelet Receptor-Mediated Factor VIII Binding. Journal of Biological Chemistry, 275(17):13071-13081.

7.   Zhang, Y., Scandura, J.M., VanNostrand,W.E. and Walsh, P.N. (1997) The Mechanism by Which Heparin Promotes the Inhibition of Coagulation Factor XIa by Protease Nexin-2. Journal of Biological Chemistry, 272(42):26139-26144.

8.   Scandura, J.M., Zhang, Y., Van Nostrand, W.E. and Walsh, P.N. (1997) Progress Curve Analysis of the Kinetics with Which Blood Coagulation Factor XIa is Inhibited by Protease Nexin-2. Biochemistry, 36(2):412-420.

9.   Scandura, J.M., Ahmad, S.S. and Walsh, P.N. (1996) A Binding Site Expressed on the Surface of Activated Human Platelets is Shared by Factor X and Prothrombin. Biochemistry, 35(27):8890-8902.

10.   Scandura, J.M. and Walsh, P.N. (1996) Factor X Bound to the Surface of Activated Human Platelets is Preferentially Activated by Platelet-bound Factor IXa. Biochemistry, 35(27):8903-8913.

11.   Walsh, P.N., Scandura, J.M. and Ahmad, S.S. (1995) Platelet-mediated Coagulation Protease Assembly. Proceedings from the National Antithrombin Investigators Meeting, Naples, Florida.

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