George S. Alexopoulos, M.D.

Psychiatry

Publications

SELECTED PUBLICATIONS

Alexopoulos, G.S., Vrontou, C., Kakuma, T., Meyers, B.S., Young, R.C., Klausner, E., Clarkin, J. "Disability in Geriatric Depression." Am J Psychiatry vol.153 (1996): 877-885.   

Alexopoulos, G.S., Meyers, B.S., Young, R.C., Campbell, S., Sibersweig, D., Charlson, M. "The 'Vascular Depression' Hypothesis." Arch Gen Psychiatry vol.54 (1997): 915-922.

Alexopoulos, G.S., Meyers, B.S., Young, R.C., Kakuma, T., Silbersweig, D., Charlson, M. "Clinically Defined Vascular Depression." Am J Psychiatry vol.154 (1997): 562-565.

Alexopoulos, G.S., Bruce, M.L., Hull, J., Kakuma, T. "Clinical Determinants of Suicidal Ideation and Behavior in Geriatric Depression." Arch Gen Psychiatry vol.56 (1999): 1048-1053.

Alexopoulos GS, Raue P, Arean P: Problem-solving therapy in geriatric depression with executive dysfunction. Am J Geriatr Psychiatry 11:46-52, 2003.

Alexopoulos GS: On the "infallibility" of sciences of psychopathology and its implications for action. Am J Psychiatry 161:2151-2154, 2004.

Alexopoulos GS, Streim J, Carpenter D, Docherty JP: The Expert Consensus Guideline Series: Using Antipsychotic Agents in Older Patients. J Clin Psychiatry 65 (suppl 2): 1-105, 2004.

Bruce ML, Ten Have TR, Reynolds III CF, Katz IR, Schulberg HC, Mulsant BH, Brown GK, McAvay GJ, Pearson JL, Alexopoulos GS: Reducing suicidal Ideation and depressive symptoms In depressed older primary care patients. A randomized controlled trial. JAMA 291:1081-1091, 2004.

Alexopoulos GS, Kiosses DN, Murphy C, Heo M: Executive dysfunction, heart disease burden, and remission of geriatric depression. Neuropsychopharmacol 29: 2278-2284, 2004.

Alexopoulos GS, Katz IR, Bruce ML, Heo M, Have TT, Raue P, Bogner HR, Schulberg HC, Mulsant BH, Reynolds CF 3rd.: Remission in Depressed Geriatric Primary Care Patients: A Report From the PROSPECT Study. Am J Psychiatry 162:718-724, 2005.

Alexopoulos GS:  Depression in the elderly. Lancet 365:1961-70, 2005.

Alexopoulos GS, Kiosses N, Heo M, Murphy CF, Shanmugham B, Gunning-Dixon F: Executive dysfunction and the course of geriatric depression. Biol Psychiatry 58:204-210, 2005.

Alexopoulos GS, Sirey J, Raue PJ, Kanellopoulos D, Clark TE, Novitch RS: Outcomes of depressed patients undergoing inpatient pulmonary rehabilitation. Am J Geriatr Psychiatry 14:466-475, 2006.

Barnes DE, Alexopoulos GS, Lopez OL, Williamson JD, Yaffe K: Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the cardiovascular health study. Arch Gen Psychiatry 63:273-279, 2006.

Alexopoulos GS, Murphy CF, Gunning-Dixon FM, Kalayam B, Katz R, Kanellopoulos D, Etwaroo GR, Klimstra S, Foxe JJ: Event-related potentials in an emotional go/no-go task and remission of geriatric depression. Neuroreport 18:217-21, 2007.

Alexopoulos GS, Kanellopoulos D, Murphy C, Gunning-Dixon F, Katz R, Heo M: Placebo response and antidepressant response. Am J Geriatr Psychiatry 15:149-58, 2007.

Alexopoulos GS, Murphy CF, Gunning-Dixon FM, Latoussakis V, Kanellopoulos D, Klimstra S, Lim KO, Hoptman MJ:  Microstructural white matter abnormalities and remission of geriatric depression.  Am J Psychiatry 165(2):238-44, 2008.

Alexopoulos GS, Murphy CF, Gunning-Dixon FM, Glatt CE, Latoussakis V, Kelly RE Jr, Kanellopoulos D, Klimstra S, Lim KO, Young RC, Hoptman MJ:  Serotonin transporter polymorphisms, microstructural white matter abnormalities and remission of geriatric depression. J Affect Disord 119:132-141, 2009.
 
Alexopoulos GS, Glatt CE, Hoptman MJ, Kanellopoulos D, Murphy CF, Kelly RE Jr, Morimoto SS, Lim KO, Gunning FM: BDNF Val66met polymorphism, white matter abnormalities and remission of geriatric depression. J Affect Disord Sep;125(1-3):262-8, 2010.
 
Alexopoulos GS, Morimoto SS: The inflammation hypothesis in geriatric depression. Int J Geriatr Psychiatry 26:1109-18, 2011.
 
Alexopoulos GS, Raue PJ, Kiosses DN, Mackin RS, Kanellopoulos D, McCulloch C, Arean PA: Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: Effect on disability. Arch Gen Psychiatry, Jan 68(1):33-41, 2011.
 
Alexopoulos GS, Hoptman MJ, Kanellopoulos D, Murphy CF, Lim KO, Gunning FM: Functional connectivity in the cognitive control network and the default mode network in late-life depression. J Affect Disord, 139(1):56-65, 2012.
 

 

 

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