Babette Barbash Weksler, M.D.

Hematology

Publications

RECENT PUBLICATIONS: 2006-2007

Weksler, Babette B: Neurologic Manifestations of Hematologic Disease, in Gilman S (ed) Neurobiology of Disease, Elsevier Academic Press, Burlington MA, San Diego CA and London, UK 2007. Ch. 59 pp.649-58.

Wei Yin , Berhane Ghebrehiwet , Babette Weksler , Ellinor I Peerschke Classical pathway complement activation on human endothelial cells. Mol Immunol. 2007 44:2228-34

B B Weksler Review article: the pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease. Aliment Pharmacol Ther. 2007 Nov;26 Sup 1: 13-19

Wei Yin , Berhane Ghebrehiwet , Babette Weksler , Ellinor I B Peerschke

Regulated complement deposition on the surface of human endothelial cells: Effect of tobacco smoke and shear stress. Thromb Res. 2007 Dec 29 (e-published ahead of print)

Daniel Catanzaro , Ying Zhou , Rong Chen , Fangmin Yu , Sarah Catanzaro , Mariana De Lorenzo , Kotha Subbaramaiah , Xi Zhou , Domenico Pratico , Andrew Dannenberg , Babette Weksler Potentially Reduced Exposure Cigarettes Accelerate Atherosclerosis: Evidence for the Role of Nicotine. Cardiovasc Toxicol. 2007:192-201

Nathalie Gallay , Ludovic Anani , Adriana Lopez , Philippe Colombat , Christian Binet , Jorge Domenech , Babette B Weksler , Fabio Malavasi , Olivier Herault:

The Role of Platelet/Endothelial Cell Adhesion Molecule 1 (CD31) and CD38 Antigens in Marrow Microenvironmental Retention of Acute Myelogenous Leukemia Cells. Cancer Res. 2007;67:8624-32

Luca Cucullo , Pierre-Olivier Couraud , Babette Weksler , Ignacio-Andres Romero , Mohammed Hossain , Edward Rapp , Damir Janigro Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies. J Cereb Blood Flow Metab. 2007 Jul 4 (e-published ahead of print)

Philippe Vicente Afonso , Simona Ozden , Marie-Christine Prevost , Christine Schmitt , Danielle Seilhean , Babette Weksler , Pierre-Olivier Couraud , Antoine Gessain , Ignacio Andres Romero , Pierre-Emmanuel Ceccaldi: Human Blood-Brain Barrier Disruption by Retroviral-Infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-Junction Disorganization. J Immunol. 2007, 179:2576-2583

Imola Wilhelm , Attila Farkas , Péter Nagyőszi , György Váró , Zoltán Bálint , Gergely Végh , Pierre-Olivier Couraud , Ignacio Romero , Babette Weksler , István Krizbai

Regulation of cerebral endothelial cell morphology by extracellular calcium. Phys Med Biol. 2007;52:6261-6274

Gerty Schreibelt , Gijs Kooij , Arie Reijerkerk , Ruben van Doorn , Sonja I Gringhuis , Susanne van der Pol , Babette B Weksler , Ignacio A Romero , Pierre-Olivier Couraud , Jörg Piontek , Ingolf E Blasig , Christine D Dijkstra , Eric Ronken , Helga E de Vries

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling. FASEB J 2007, 21:3336-76

Silvia S Barbieri , Babette B Weksler Tobacco smoke cooperates with interleukin-1 beta to alter b-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo. FASEB J. 2007, 21:1831-43.

Ellinor I Peerschke, Richard T Silver, Babette B Weksler, Wei Yin, Bernard Bernhardt, David Varon : Examination of Platelet Function in Whole Blood Under Dynamic Flow Conditions With the Cone and Plate(let) Analyzer: Effect of Erythrocytosis and Thrombocytosis. Am J Clin Pathol. 2007 ;127:422-28.

Marika Massaro, Aida Habib, Laura Lubrano, Serena Del Turco, Guido Lazzerini, Todd Bourcier, Babette B Weksler, Raffaele De Caterina: The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCe inhibition. Proc Natl Acad Sci USA. 2006, 103:15184-9.

Sharon A Savage , Brian J Stewart , Babette B Weksler , Gabriela M Baerlocher , Peter M Lansdorp , Stephen J Chanock , Blanche P Alter: Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood Cells Mol Dis. 2006: 16934504

Alter BP, Baerlocher GM, Savage SA, Chanock SJ, Weksler BB, Willner JP, Peters JA, Giri N, Lansdorp PM. Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood. 2007 110:1439-47.

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