Publications
Weksler M, Goodhardt M. Do age-associated changes in 'physiologic' autoantibodies contribute to infection, atherosclerosis, and Alzheimer's disease? Exp Gerontol. 37:971 2002Li F, Yarilin DA, Valiando J, Ronco A, Weksler ME, Szabo P, Posnett DN. Tumor antigen drives a persistent oligoclonal expansion of CD8 T cells in aged mice. Eur J Immunol. 32:1650-8 2002.Weksler ME, Relkin N, Turkenich R, LaRusse S, Zhou L, Szabo P. Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals. Exp Gerontol. 37:943-8 2002Weksler ME, Goodhardt M, Szabo P. The effect of age on B cell development and humoral immunity. Springer Semin Immunopathol. 24:35-52. 2002Posnett DN, Yarlin D, Valiando JR, Li F, Liew FY, Weksler, ME, Szabo, P, Oligoclonal Expansions of Antigen-Specific CD8 T cells in Aged Mice. Ann. NY Acad. Sci. 987:1-6, 2003Szabo P, Shen, S., Telford, W., Weksler, ME Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice. Cell. Immunol. 222:78-87, 2003
Li F, Yarilin DA, Valiando J, Ronco A, Weksler ME, Szabo P, Posnett DN. Tumor antigen drives a persistent oligoclonal expansion of CD8 T cells in aged mice. Eur J Immunol. 32:1650-8 2002.
Weksler ME, Relkin N, Turkenich R, LaRusse S, Zhou L, Szabo P. Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals. Exp Gerontol. 37:943-8 2002
Weksler ME, Goodhardt M, Szabo P. The effect of age on B cell development and humoral immunity. Springer Semin Immunopathol. 24:35-52. 2002
Posnett DN, Yarlin D, Valiando JR, Li F, Liew FY, Weksler, ME, Szabo, P, Oligoclonal Expansions of Antigen-Specific CD8 T cells in Aged Mice. Ann. NY Acad. Sci. 987:1-6, 2003
Szabo P, Shen, S., Telford, W., Weksler, ME Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice. Cell. Immunol. 222:78-87, 2003
Weksler, ME The Immunotherapy of Alzheimer’s Disease Immunity and Aging 1:2-10, 2004
Szabo, P, Li, F, Mathew, J., Lillvis, J, Weksler, M.E. Evolution of B-cell clonal expansions with age. Cell. Immunol. 231:158-67, 2004
Paul, S. Nishiyama, Y, Planque, S., Karle S, Taguchi, Hanson, C, Weksler, ME, Antibodies as Defensive Enzymes, Springer Seminars Immunopathol. 26:485-503, 2005.
Weksler M. E., Gouras, G. Relkin, N.R., Szabo, P. The Immune System, Amyloid-beta Peptide, and Alzheimer’s Disease, Immunol. Reviews 205:244-56, 2005
Szabo P, Relkin N, Weksler ME. Natural human antibodies to amyloid beta peptide. Autoimmun Rev. 2008 Jun;7(6):415-20.
Taguchi H, Planque S, Nishiyama Y, Szabo P, Weksler ME, Friedland RP, Paul S
Catalytic antibodies to amyloid beta peptide in defense against Alzheimer disease. Autoimmun Rev. 2008 May;7(5):391-7.
Relkin NR, Szabo P, Adamiak B, Burgut T, Monthe C, Lent RW, Younkin S, Younkin L, Schiff R, Weksler ME. 18-month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol Aging. 2008 Feb 20. [Epub ahead of print]
Taguchi H, Planque S, Nishiyama Y, Symersky J, Boivin S, Szabo P, Friedland RP, Ramsland PA, Edmundson AB, Weksler ME, Paul S. Autoantibody-catalyzed hydrolysis of amyloid beta peptide. J Biol Chem. 2008 Feb 22;283(8):4714-22.
Weksler, ME, Pawelec G, Franceschi C. Immune therapy for age-related diseases Trends in Immunology, in press, 2009
