Publications
1. Beadling,,C. and Smith,K.A. DNA array analysis of interleukin-2-regulated immediate/early genes. Medical Immunology 1:2, 2002.
2. Blattman, J.N., Grayson, J.M., Wherry, E.J., Kaech, S.M., Smith, K,A., Ahmed, R. Therapeutic use of IL2 to enhance antiviral T cell responses in vivo. Nature Med. 9:1-8, 2003.
3. Smith, K.A. The quantal theory of how the immune system discriminates between #147;self and non-self#148;. Med Immunol. 3:3, 2004.
4. Nasca, J., Edghill-Smith, Y., Tsai, W-P., Venzon, D., Tryniszewska, E., Hryniewicz, A., Moniuszko, M., Kinter, A., Smith, K.A., Franchini, G. Contrasting effects of low-dose IL2 on vaccine-boosted Simian Immunodeficiency Virus (SIV)-specific CD4 and CD8 T cells in macaques chronically infected with SIVmac251. J Immunol. 174:1913-1921, 2005.
5. Smith, K.A. The structure of IL2 bound to the three chains of the IL2 receptor and how signaling occurs. Med. Immunol. 5:3, 2006.
6. Smith, K.A., Andjelic, S., Popmihajlov, Z., Kelly-Rossini, L., Sass, A., Lesser, M., Benkert., S., Waters, C., Ruitenberg, J., Bellman, P. Immunotherapy with canarypox vaccine and interleukin-2 for HIV-1 infection: Termination of a randomized trial. PLoS Clinical Trials. January, 2007, e5
7. Popmihajlov, Z., and Smith, K.A. Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity. PLoS One. 3(2): e1581, 2008.
8. Smith, K.A. and Z. Popmihajlov. The quantal theory of immunity and the interleukin-2-dependent negative feedback regulation of the immune response. Immunol. Rev. 224: 124-140, 2008.
9. Ha, S-J., West, E.E., Araki, K., Smith, K.A., and Ahmed., R. Manipulating both inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunol. Rev. 224: 317-333, 2008.
10. Smith, K.A. and Griffin, J.D. Following the cytokine signaling pathway to leukemogenesis: A chronology. J. Clin. Invest. 124:1-10, 2008.
11. Kalia, V., Sarkar, S., Subramanian, S., Haining, W.N., Smith, K.A. and Ahmed, R. Prolonged interleukin2R alpha expression on virus-specific Cd8+ T cells favors terminal effector differentiation in vivo. Immunity. 32:91-103, 2010.
12. Margolick, J.B., Imteyaz, H., Gallant, J.E., Langan, S.J., Dinoso, J.B., Silicano, J., Blankson, J., Nilles, T.L., Smith, K.A., and Apuzzo, L.G. AIDS. 24: 932-935., 2010.
13. Feinerman, O., Jentsch, G., Tkach, K.E., Coward, J.W., Hathorn, M.W., Sneddon, M.W., Emonet, T., Smith, K.A., and Altan-Bonnet, G. Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol. Syst. Biol. 6:1-16, 2010.
14. Liou, H-C., and Smith, K.A., The roles of c-Rel and interleukin-2 in tolerance: a molecular explanation of self-nonself discrimination. Immunol. Cell Biol. 1-6, Oct. 26, 2010
15. Smith, K.A. The Quantal Theory of Immunity: The Molecular Basis of Autoimmunity and Leukemia. World Scientific Publishing Co. Pte., Ltd. Singapore, 235 pp. 2010.
