Publications

Recent articles, books, book chapters and reviews (published or in press)

  1. Acharya SS, Coughlin A, DiMichele DM and the North American Rare Bleeding Disorders Study Group. Rare Bleeding Disorder Registry: Deficiencies of Factors II, V, VII, X, XIII, Fibrinogen and Dysfibrinogenemias. The Journal of Thrombosis and Haemostasis, 2:248-256, 2004.
  2. DiMichele D, Rivard G, Antunes, S. Inhibitors in Haemophilia #150; Clinical Aspects. Haemophilia, 10 (s4) 140 #150; 145, 2004.
  3. DiMichele D. In Praise of Long-term Prospective Data Collection: Questions and Perspectives. The Journal of Thrombosis and Haemostasis, 2:1044-1046, 2004.
  4. Schrijver I, Hong DW, Mandle L, Jones CD, DiMichele D, Monahan PE, Zehnder JL. High Frequency of Premature Termination Mutations in the Factor V Gene: Three Factor V Deficiency Case Reports and a Mutation Review. Thrombosis and Haemostasis, in press.
  5. DiMichele DM. Gene therapy for hemophilia? The Journal of Thrombosis and Haemostasis, 3(6) 1315-1316, 2005.
  6. Berntorp E, Astermark J, Donfield SM, Nelson GW, Oldenburg J, Shapiro AD, DiMichele DM, Ewenstein BM, Gomperts ED, Winkler CA. Hemophilia Inhibitor Genetics Study (HIGS)#151;Evaluation of a Model for Studies of Complex Diseases Using Linkage and Association Methods. Haemophilia, 11:427-429, 2005.
  7. DiMichele DM. Management of FVIII Inhibitors. International Journal of Hematology, in press.
  8. DiMichele D and Negrier C. A Retrospective Post-Licensure Survey of FEIBA Efficacy and Safety. Haemophilia, in press.
  9. DiMichele DM: Inhibitors to Factor VIII: Epidemiology and Treatment. TEXTBOOK OF HEMOPHILIA. (Lee C, Hoots K and Berntorp E, eds), Blackwell Publishing, 2004.
  10. Brandao LR, DiMichele DM: Disorders of Coagulation in the Neonate. HEMATOLOGY: BASIC PRINCIPLES AND PRACTICE. (4th Edition. Hoffman R, Benz Jr EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE and McGlave P, eds), Elsevier Science, 2005.
  11. DiMichele DM: Inhibitors to Factor VIII: Epidemiology and Treatment. TEXTBOOK OF HEMOPHILIA. (Lee C, Hoots K and Berntorp E, eds), Blackwell Publishing, 2004.
  12. Brandao LR, DiMichele DM: Disorders of Coagulation in the Neonate. HEMATOLOGY: BASIC PRINCIPLES AND PRACTICE. (4th Edition. Hoffman R, Benz Jr EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE and McGlave P, eds), Elsevier Science, 2005.
  13. Acharya SS, DiMichele DM: Management of Factor VIII Inhibitors. BEST PRACTICE AND RESEARCH CLINICAL HAEMATOLOGY. (Francis CW, Blumberg N, Heale, J eds), Elsevier Science, 19(1):51-66, 2006.
  14. DiMichele DM. Management of FVIII Inhibitors. International Journal of Hematology. 2006; 83(2):119-125.
  15. DiMichele D, Chuansumrit A, London AJ, Thompson AR, Cooper CG, Killian RM, Ross LF, Lillicrap D, Kimmelman J. Ethical Issues in Hemophilia. Haemophilia. 2006;12;(s3)30-5.
  16. DiMichele DM and Negrier C. A Retrospective Postlicensure Survey of FEIBA Efficacy and Safety. Haemophilia. 2006; 12(4):352-362.
  17. Mannucci PM, Abshire T, DiMichele D, Santagostino E, Blanchette V. Inhibitor development, immune tolerance and prophylaxis in haemophilia A #150; the need for an evidence-based approach. Haemophilia. 2006 Jul;12(4):429-34.
  18. DiMichele DM and Hay Charles RM. The International Immune Tolerance Study: A Multicenter Prospective Randomized Trial in Progress. J Thromb Haemost. 2006 Oct 4;(10):2271-3.
  19. DiMichele DM. Factor VIII Pharmacokinetics: Impact of low titer non-neutralizing inhibitors and use in determination of successful immune tolerance. Haemophilia, 12; (s4) 56-60, 2006.
  20. DiMichele D. Inhibitor Treatment in Hemophilia A and B: Inhibitor Diagnosis. Haemophilia, 2006, 12(Suppl. 6).
  21. DiMichele D. Immune Tolerance: Critical Issues of Factor Dose, Purity and Treatment Complications. Haemophilia, 2006, 12(Suppl. 6), 1-6.
  22. Astermark J, Donfield S, DiMichele D, Gringeri A, Gilbert S, Waters J and Berntorp E for the FENOC Study Group. A Randomized Comparison of Bypassing Agents in Hemophilia Complicated by an Inhibitor: The FEIBA NovoSeven Comparative Study (FENOC). Blood, 2007;109(2):546-51.
  23. DiMichele D. Immune tolerance therapy for factor VIII inhibitors: moving from empiricism to an evidence-based approach. J Thromb Haemost, 2007; 5 (Suppl.1):1-8.
  24. DiMichele DM, Hoots K, Pipe SW, Rivard GE, Santagostino. International workshop on immune tolerance induction: consensus recommendations. Haemophilia, 2007;13(S1):1-22.
  25. DiMichele D. Inhibitor development in haemophilia B: an orphan disease in need of attention. Br J Haematol. 2007; 138(3):305-15.
  26. Manco-Johnson MJ, Abshire TC, Shapiro AD, Riske B, Hacker MR, Kilcoyne R, Ingram D, Manco-Johnson ML, Funk S, Jacobson L, Valentino LA, Hoots KW, Buchanan GR, DiMichele D, Recht M, Brown D, Leissinger C, Bleak S, Cohen A, Mathew P, Matsunga A, Medeiros D, Nugent D, Thomas GA, Thompson AA, McRedmond K, Soucie JM, Austin H, Evatt BL. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. NEMJ 2007;357(6):535-544.
  27. Brandão LR, Long GL, Wentworth C, Block K, Gibb CB, DiMichele DM. Severe homozygous protein C deficiency: atypical clinical presentation in association with homozygosity for the OSAKA 4 PROC mutation. Submitted to J Ped Blood and Cancer, 2007.
  28. Brandão LR, Kletzel M, Boulad F, Kurtzberg, Maloney K, Fligman I, Sison CP, DiMichele DM. A prospective longitudinal mlticenter study of coagulation in pediatric patients undergoing allogenic stem cell transplantation. Submitted to J Ped Blood and Cancer, 2007.
  29. Greninger DA, Saint-Remy JM, Jacquemin M, Benhida A, DiMichele DM. The use of factor VIII/concentrate for immune tolerance induction in hemophilia A patients with high titer inhibitors: Association of clinical outcome with inhibitor epitope profile. Submitted to J Thromb Haemost, 2007.

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