Publications
Selected recent:
-Moscona A. Entry of parainfluenza virus into cells as a target for interrupting childhood respiratory disease. The Journal of Clinical Investigation 115: 1688-1698, 2005.
-Moscona A. Neuraminidase inhibitors for influenza. New England Journal of Medicine 353:1363-1373, 2005.
-Moscona A. Oseltamivir resistance – Disabling our influenza defenses. New England Journal of Medicine 353: 2633-2636, Dec 22, 2005.
-Porotto M, Fornabaio M, Greengard O, Murrell MT, Kellogg GE, Moscona A. Paramyxovirus receptor-binding molecules: Engagement of one site on the hemagglutinin-neuraminidase protein modulates activity at the second site. Journal of Virology 80 (3): 1204-1213, 2006.
-Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg GE, Moscona A. Inhibition of Hendra virus fusion. Journal of Virology 80 (19): 9837-9849, 2006.
-Porotto M, Fornabaio M, Kellogg GE, Moscona A. A second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanism. Journal of Virology 81(7): 3216-28, 2007.
-Palermo LM, Porotto M, Greengard O, and Moscona, A. Fusion promotion by a paramyxovirus hemagglutinin-neuraminidase protein: pH modulation of receptor avidity of binding sites I and II by pH. Journal of Virology 81 (17), 9152-9161, 2007.
-Porotto M, Carta P, Deng Y, Kellogg GE, Whitt M, Lu M, Mungall BA, Moscona, A. Molecular determinants of antiviral potency of paramyxovirus entry inhibitors. Journal of Virology 81 (19): 10567-74, 2007.
-Porotto M, Orefice G, Yokoyama C, Mungall B, Realubit R, Sganga M, Aljofan M, Whitt M, Glickman F, and Moscona A. Simulating henipavirus multicycle replication in a screening assay leads to identification of a promising candidate for therapy. Journal of Virology May; 83(10):5148-55, 2009. .
-Moscona A. Global Transmission of Oseltamivir-Resistant Influenza. New England Journal of Medicine Mar 5; 360(10):953-6, 2009.
-Porotto M, Yokoyama C, Orefice G, Kim HS, Aljofan M, Mungall B, Moscona A. Kinetic dependence of paramyxovirus entry inhibition. Journal of Virology. July; 83 (13): 6947-6951, 2009.
-Palermo L, Porotto M, Yokoyama C, Palmer S, Mungall B, Greengard O, Niewiesk S, and Moscona A. Human parainfluenza virus infection of the airway epithelium: the viral hemagglutinin-neuraminidase regulates fusion protein activation and modulates infectivity. Journal of Virology 83 (13): 6900-6908, 2009.
-Moscona A, Porotto M, Palmer S, Tai C, Aschenbrenner L, Triana-Baltzer G, Li H, Wurtman D, Niewiesk S, Fang F.. A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. Journal of Infectious Diseases 202 (2): 234-241, 2010.
-Porotto M, Yokoyama C, Palermo LM, Mungall B, Aljofan M, Cortese R, Pessi A, and Moscona A. Viral entry inhibitors targeted to the membrane site of action. Journal of Virology 84 (13): 6760-6768, 2010.
-Porotto M, Rockx B.,Yokoyama CC, Talekar A., DeVito I.,Palermo LM, , Cortese R, Lu M., Feldmann H., Pessi A, Moscona A Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry. PLoS Pathogens 6 (10): e1001168. doi:10.1371/journal.ppat.1001168, 2010.
-Porotto M, Yi F, Moscona A, LaVan DA Synthetic Protocells Interact with Viral Nanomachinery and Inactivate Pathogenic Human Viruses. PloS One 6(3): e16874. doi:10.1371/journal.pone.0016874.
