Publications
Schafer AI. Deficiency of platelet lipoxygenase activity in myeloproliferative disorders. N Engl J Med. 1982; 306:38l‑6.
Corey EJ, Pyne SG, Schafer AI. Synthesis of a new series of potent inhibitors of thromboxane A2 biosynthesis. Tetrahedron Lett. 1983; 24:3291‑4.
Schafer AI, Adelman B. Plasmin inhibition of platelet function and of arachidonic acid metabolism. J Clin Invest. 1985; 75:456‑61.
Tofler GH, Brezinski D, Schafer AI, Czeisler CA, Rutherford JD, Willich SN, Gleason RE, Williams GH, Muller JE. Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death. N Engl J Med. 1987; 316:1514‑8.
Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand factor binding to platelet GpIb initiates signals for platelet activation. J Clin Invest. 1991; 88:1568–1573.
Schafer AI. Hypercoagulable states: molecular genetics to clinical practice. Lancet. 1994; 344:1739–1742.
Schafer AI. Vascular endothelium: in defense of blood fluidity (ed). J Clin Invest. 1997; 99:1143–44.
Durante W, Liao L, Reyna S, Peyton KJ, Schafer AI. Physiological cyclic stretch directs L-arginine transport and metabolism to collagen synthesis in vascular smooth muscle cells. FASEB J. 2000; 14:1775-1783.
Tulis DA, Durante W, Liu XM, Evans AJ, Peyton KJ, Schafer AI. Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation 2001; 104:2710-2715.
Schafer AI. Walking the tightrope of anticoagulant dosing. N. Engl J Med. 2003; 348:1478-80.
Schafer AI. Thrombocytosis. N Engl J Med 2004; 350:1211-19.
Schafer AI. Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia. Blood 2006; 107:4214-4222.
Jiang XH, Yang F, Brailoiu E, Jakubowski H, Dun NJ, Schafer AI, Yang XF, Durante W, Wang H. Differential regulation of homocysteine transport in vascular endothelial and smooth muscle cells. Arterioscler Thromb Vasc Bio 2007; 27:1976-1983.
Jamaluddin MS, Chen I, Yang F, Jiang XH, Jan M, Liu X, Schafer AI, Durante W, Yang XF, Wang H. Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood 2007; 110: 3648-3655.
Hasan RN, Schafer AI. Hemin upregulates Egr-1 expression in vascular smooth muscle cells via ROS, ERK1/2 and Elk-1. Circ Res 2008; 102: 42-50.
